“Muscle breakdown” from heavy but unfit exercise, beware of “acute renal failure”

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Kidney failure has become a silent threat nowadays because there are many factors that trigger the disease to increase. The เล่น UFABET ผ่านมือถือ สะดวกทุกที่ ทุกเวลา, Ministry of Public Health revealed that Thailand has 11.6 million chronic kidney patients and more than 100,000 people need dialysis. And from the report of The United States Renal Data System (USRDS), it was found that Thailand is one of the 5 countries. With the highest rate of kidney disease. Kidney disease can be caused by many things, whether it is food consumption or alcoholic beverages. And another factor that many people don’t know is “rhabdomyolysis.” What is this condition?

It is reported that approximately 25,000 cases of rhabdomyolysis occur in the United States each year, with 5-30% of cases developing acute renal failure and accounting for 15% of all acute renal failure cases. 

Rhabdomyolysis is a serious medical condition in which muscle tissue breaks down due to direct muscle injury or from excessive muscle exertion, particularly in long-distance running and downhill running . Rhabdomyolysis can also be caused by compression injuries, as well as the effects of certain medications and genetics.

Who can experience rhabdomyolysis ?

  • It can occur at any age, but it is most common in males and African-Americans.
  • People with obesity
  • Over 60 years old

The mortality rate without renal failure is approximately 20% and mortality as high as 50% in patients with acute renal failure from rhabdomyolysis. Interestingly, 10-30% of rhabdomyolysis cases are caused by exercise-induced muscle injury.

The causes of rhabdomyolysis can be divided into two main categories as follows:

  • Physical causes 
  • Runners who suddenly increase their training intensity after a period of conditioning, such as recovering from an illness or taking a break from training.  
  • Exercising or doing strenuous exercise, such as running a marathon
  • Competing at a higher intensity and for longer periods than previously practiced 
  • Training or competing while dehydrated, on hot days or with hypothermia for extended periods.
  • Severe injuries to muscles in the form of crushing, compression, or pressing (Crush injury), such as car accidents and landslides. 
  • Persistent seizures, such as in epilepsy 

Non-physical causes 

  • The effects of taking statins to lower cholesterol, antihistamines, anti-nausea drugs, and psychiatric drugs, including pain relievers and nonsteroidal anti-inflammatory drugs (NSAIDS).       
  • Viral or bacterial infections, endocrine problems, electrolyte imbalances   
  • Genetic disorders 
  • Ischemic conditions such as prolonged bedridden conditions
  • Drinking alcohol
  • Surgery or anesthesia  

Warning signs of rhabdomyolysis

  • Muscle pain, weakness
  • Decreased urination or urine that looks like coke 

There are also other symptoms that may appear 24 to 48 hours after exercise, such as:

  • Irregular heart rate
  • Joint pain
  • confused
  • Elevated body temperature 
  • Nausea, vomiting 
  • Dehydration 
  • stomach ache 
  • CK enzyme levels increase 5-10 times from normal levels (can only be measured by blood test)

Treatment of rhabdomyolysis

In patients with rhabdomyolysis, intravenous fluid administration should be initiated as soon as possible. Delays in resuscitation may result in hypovolemic shock. Up to 10–20 L of fluid should be administered to maintain intravascular hydration and promote urinary excretion. When hospitalized, close monitoring of urine output and daily sequential monitoring of CK levels are essential. Rhabdomyolysis is associated with renal dysfunction, imbalances of potassium, calcium, uric acid, and phosphate, and electrolyte balance is essential.

How to take care of yourself to maintain balance and avoid kidney failure from exercise

  • Avoid drinking alcoholic beverages, especially before exercise.
  • If you are running a long distance, you must practice and be physically fit.
  • Don’t overdo it. Make sure you train enough so that your body can handle the intense exercise.
  • Do not let your body become dehydrated.
  • Get your potassium boost during strenuous exercise by eating a banana and drinking an electrolyte-fortified drink.